Topic

CRISPR

1 post about CRISPR. Every summary links to the original.

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Anthropic
Claude discovers a novel enzyme system
Anthropic launched a new life sciences research group to use AI agents for fundamental biology discovery. In one of their first programs, Claude agents autonomously analyzed over 200,000 reverse transcriptase sequences from a DNA database. After 21 hours and 210 million tokens, one agent spotted a repeating DNA pattern next to a reverse transcriptase gene, which it identified as a CRISPR-like system. The system, called ART (array-associated reverse transcriptases), consists of the RT, an accessory protein, and an array of non-coding DNA repeats that are expressed as distinct small RNAs. Its function remains unknown, but the pattern of repeats is only found together in other programmable DNA-cutting systems, suggesting ART may be a new tool for biotechnology.

The best engineering reads, once a week.

Topic

1 post about CRISPR. Every summary links to the original.

Paid picks we use ourselves. Links carry a referral code — a subscription through one earns us a commission at no extra cost to you.

Newest first

Anthropic
Claude discovers a novel enzyme system
Anthropic launched a new life sciences research group to use AI agents for fundamental biology discovery. In one of their first programs, Claude agents autonomously analyzed over 200,000 reverse transcriptase sequences from a DNA database. After 21 hours and 210 million tokens, one agent spotted a repeating DNA pattern next to a reverse transcriptase gene, which it identified as a CRISPR-like system. The system, called ART (array-associated reverse transcriptases), consists of the RT, an accessory protein, and an array of non-coding DNA repeats that are expressed as distinct small RNAs. Its function remains unknown, but the pattern of repeats is only found together in other programmable DNA-cutting systems, suggesting ART may be a new tool for biotechnology.

The best engineering reads, once a week.